Quick view Upneeq Upneeq (oxymetazoline hydrochloride ophthalmic solution) is the only FDA-approved once-daily eyedrop for acquired ptosis (low-lying lids) that lifts your upper eyelids to open your eyes. One kit contains 45 single-patient use containers (0.3mL) MSRP: Was: Now: $225.00 Add to Cart